Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKCIKTLFLSIILVVMGGWYHSAHASDSLSKSPENWMSKLDESKHLTEINMPGSHDSGSFTLTDPVKSVWAKTQGKDYLTQMKSGVRFFDIRGRASADNMISVHHGMVYLHHELGKFLDDAKYYLSAYPNETIVMSMKKDYDSDSKVTKTFEEIFREYYYNNPQYQNLFYTGSNANPTLKETKGKIVLFNRMGGTYIKSGYGADTSGIQWADNATFETKINNGSLNLKVQDEYKDYYDKKVEAVKNLLAKAKTDSNKDN-VYVNFLSVASGGSAFNSTYNYASHINPEIAKTIKENGKARTGWLIVDYAGYPWPGYDDIVSEIIDSNK 1T6M Chain:B ((14-294)) ------------------------------------WMQPIPDNIPLARISIPGTHDSGTFKLQNPIKQVWGMTQEYDFRYQMDHGARIFDIDGRLTDDNTIVLHHGPLYLYVTLHEFINEAKQFLKDNPSETIIMSLKKEYEDMKGAEGSFSSTFEKNYFVDP-----IFLKTEGNIKLGDARGKIVLLKRYSGSNESGGY----NNFYWPDNETFTTTVNQ-NVNVTVQDKYKVNYDEKVKSIKDTMDETMNNSEDLNHLYINFTSLSSGGTAWNSPYYYASYINPEIANDIKQKNPTRVGWVIQDYINEKWSPL--LYQEVIRANK

General information: TITO was launched using: RESULT: Template: 1T6M.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -74530 for 2369 contacts (-31.5/contact) + 2D Compatibility (PS) -30518 + (NN) -15779 + (LL) 2584 1D Compatibility (HY) -24400 + (ID) 5900 Total energy: -148543.0 ( -62.70 by residue) QMean score : 0.451

(partial model without unconserved sides chains): PDB file : Tito_1T6M.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1T6M-query.scw PDB file : Tito_Scwrl_1T6M.pdb: