Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRILEKAPAKINLSLDVTRKRPDGYHEVEMIMTTIDLADRIELTELAEDEVRVSSHNRFVPDDQRNLAYQAAKLIKDRYNVKKGVSIMITKVIPVAAGLAGGSSDAAATLRGLNRLWNLNLSAETLAELGAEIGSDVSFCVYGGTALATGRGEKIKHISTPPHCWVILAKPTIGVSTAEVYRALKLDGIEHPDVQGMIEAIEEKSFQKMCS----RLGNVLESVTLDMHPEVAMIKNQMKRFGADAVLMSGSGPTVFGLVQYESKVQRIYNGLRGFCDQVYAVRMIGEQNALD 2V2V Chain:B ((9-246)) ------SPAKINLGLWVLGRLPSGYHEILTLYQEIPFYDEIYIREGV---LRVET-NIGIPQEE-NLVYKGLREFERITGIEINYSIFIQKNIPPGAGLGGGSSNLAVVLKKVNELLGSPLSEEELRELVGSISADAPFFLLGKSAIGRGKGEVLEPVETEISGKITLVIPQVSSSTGRVYSSLREEHFVTPEYA-------EEKIQRIISGEVEEIENVLGDIARELYPEINEVYRFVEYLGFKP-FVSGSGSTVY------------------------------------

General information: TITO was launched using: RESULT: Template: 2V2V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -96309 for 1943 contacts (-49.6/contact) + 2D Compatibility (PS) -25619 + (NN) -12143 + (LL) 4808 1D Compatibility (HY) -19200 + (ID) 3950 Total energy: -152413.0 ( -78.44 by residue) QMean score : 0.381

(partial model without unconserved sides chains): PDB file : Tito_2V2V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2V2V-query.scw PDB file : Tito_Scwrl_2V2V.pdb: