Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTVRYQIEQLGDSAMMIRFGEEINEQVNGIVHAAAAYIEEQPFPGFIECIPAFTSLTVFYDMYEVYKHLPQGISSPFESVKRDVEERLAEIAEDYEVNRRIVEIPVCYGGEFGPDLEEVAKINQLSPEEVIDIHTNGEYVVYMLGFAPGFPFLGGMSKRIAAPRKSSPRPSIPAGSVGIAGLQTGVYPISTPGGWQLIGKTPLALFRPQENPPTLLRAGDIVKFVRISEKDYHAYKEESN 2PHC Chain:B ((2-217)) -----IIKPAGDSAFLISFGDEISEEINDRVHSLAKAIEKESPEWLVELVPAYSSLLVIYDPLKASYEEVES------YLKRISAR----E--VERIKGKTIEIPVAYGGEFGPDIEFVAQYNGLSVDDVIEIHSKPLYRVYFLGFLPGFAYLGGMDERIATPRLEKPRLKVPAGSVGIAGKQTGWYAIESPGGWRIIGRIPLRTFNPGKVPPSIVLPGDYVKFVPIDEKEFW-------

General information: TITO was launched using: RESULT: Template: 2PHC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1051 -136874 -130.23 -633.68 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain B : 0.81 3D Compatibility (PKB) : -130.23 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.514

(partial model without unconserved sides chains): PDB file : Tito_2PHC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2PHC-query.scw PDB file : Tito_Scwrl_2PHC.pdb: