Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVYITYGTADFLKTIVQKHPSENILLMQGQENAILIHETNGDTVFQAPHAYEVIDQVGEIKHPGFAVLNNIAVTQEGRPLFENRFKNRAGKVENEPGFEAIRVLRPLDSDTYVILTLWETESAFQDWQQSGSYKEAHKKRDTSAGIDTTSIFSRPSYVTTYFAVE 4FVC Chain:B ((1-165)) MKVYITYGTADFLKTIVKKHPSENILLMQGQENAILIHETSGDTVFQAPHAYEVIDQVGEIKHPGFAVLANIAVTQEGRPLFENKFKNRAGKVENEPGFEAIRVLRPLDSDTYVILTLWETERAFQDWQQSDSY----------------SIFSRPSYVTTYFAV-

General information: TITO was launched using: RESULT: Template: 4FVC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 707 -96213 -136.09 -645.72 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain B : 0.96 3D Compatibility (PKB) : -136.09 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.96 QMean score : 0.660

(partial model without unconserved sides chains): PDB file : Tito_4FVC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4FVC-query.scw PDB file : Tito_Scwrl_4FVC.pdb: