Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAAQTDYKKQVVGILLSLAFVLFVFSFSERHEKPLVEGKKQENWHTVVDKASVKIYGSRLVE--ENKLKQKLGHKQADSILTLLKLANEKHITL 1E68 Chain:A ((1-70)) MAKEFGIPAAVAGTVLNVVEAG---GWVTTIVSILTA----------VGSGGLSLLAAAGRESIKAYLKKEIKKKGKRAVIAW-----------

General information: TITO was launched using: RESULT: Template: 1E68.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 247 -42135 -170.59 -619.63 target 2D structure prediction score : 0.40 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -170.59 2D Compatibility (Sec. Struct. Predict.) : 0.40 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.243

(partial model without unconserved sides chains): PDB file : Tito_1E68.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1E68-query.scw PDB file : Tito_Scwrl_1E68.pdb: