Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIYSKVENFINENKQNAIFTEGASHENIGRIEENLQCDLPNSYKWFLEKYG--AGGLFGVLVLGYNFDHASVVNRTNEYKEHYGLTDGLVVIEDVDYFAYCLDTNKMKDGECPVVEWDRVIGYQDTVADSFIEFFYNKIQEAKDDWDEDEDWDD 2PAG Chain:A ((1-135)) -LEEVIEQLREANEPVPVPLELPDEDQLVEIEEQLFINIPFVFKEFLLTVSDVVYGSLEPVTVTDPQSHTYLPEVCATAWDL-GVPRELIPICQDGEDYYCVEEDG------TVLLWSA---------LVTEESWESVWHWARDVWLES-----

General information: TITO was launched using: RESULT: Template: 2PAG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 603 -4875 -8.08 -37.50 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -8.08 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.460

(partial model without unconserved sides chains): PDB file : Tito_2PAG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2PAG-query.scw PDB file : Tito_Scwrl_2PAG.pdb: