Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHRLLLLMMLTALGVAGCGQKKPPDPPNRVPEKKVVETSAFGHHVQLVNREGKAVGFIEIKESDDEGLDIHISANSLRPGASLGFHIYEKGSCVRPDFESAGGPFNPLNKEHGFNNPMGHHAGDLPNLEVGADGKVDVIMNAPDTSLKKGSKLNILDEDGSAFIIHEQADDYLTNPSGNSGARIVCGALLGNNEKQ 1XTL Chain:C ((19-170)) ---------------------------------------AFGHHVQLVNREGKAVGFIEIKESDDEGLDIHISANSLRPGASLGFHIYEKGSCVRPDFESAGGHFNPLNKEHGFNNPMGHHAGDLPNLEVGADGKVDVIMNAPDTSLKKGSKLNILDEDGSAFIIHEQADDYLTNPSGNSGARIVCGALLG-----

General information: TITO was launched using: RESULT: Template: 1XTL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 847 -74590 -88.06 -490.72 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain C : 0.90 3D Compatibility (PKB) : -88.06 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.90 QMean score : 0.580

(partial model without unconserved sides chains): PDB file : Tito_1XTL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XTL-query.scw PDB file : Tito_Scwrl_1XTL.pdb: