Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---MNTAYRVWDGEQMHYWDDEGLSLIIKSNGDWTLKRLYTDVLVPVVDSTNRNAALMWGAKVRGKFIYDRSIVKITSDDKESSDV-CEVKFSDGVFQVDVSKISADYDVT--AV-GWVEYATIEVIGDVYQNPELLEGVK 2WQ4 Chain:A ((2-135)) PLLSASIVSAPVVTSETYVDIPGLYLDVAKAGI-RDGKLQVILNVPTPYATGNNFPGIYFAIATNQGVVADGCFTYSSKVPESTGRMPFTLVATIDVGSGVTFVKGQWKSVRGSAMHIDSYASLSAIWGTAAPSS------

General information: TITO was launched using: RESULT: Template: 2WQ4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 692 -849 -1.23 -6.68 target 2D structure prediction score : 0.40 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -1.23 2D Compatibility (Sec. Struct. Predict.) : 0.40 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.051

(partial model without unconserved sides chains): PDB file : Tito_2WQ4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2WQ4-query.scw PDB file : Tito_Scwrl_2WQ4.pdb: