Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNMDFNLFMNDIVRQARQEITAAGYTELKTAEEVDEALT---KKGTTLVMVNSVCGCAG-GIARPAAYHSVHYDKRPDQLVTVFAGQDKEATARARDYFEGYPPSSPSFAILKDGKIMKMVERHEIEGHEPMAVVAKLQEAFEEYCEEV 1EP7 Chain:A ((5-109)) -------------------------IVIDSKAAWDAQLAKGKEEHKPIVVDFTATWCGPCKMIAPLFETLSN--DYAGK--VIFLKVDVDAVAAVAEAAG--ITAMPTFHVYKDGVKAD-----DLVGASQDKLKALVAKH--------

General information: TITO was launched using: RESULT: Template: 1EP7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 410 -2660 -6.49 -26.33 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -6.49 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.555

(partial model without unconserved sides chains): PDB file : Tito_1EP7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1EP7-query.scw PDB file : Tito_Scwrl_1EP7.pdb: