Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSELFSVPYFIENLKQHIEMNQSEDKIHAMNSYYRSVVSTLVQDQLTKN-------AVVLKRIQHLDEAYNKVKRGESK 3AG7 Chain:A ((602-650)) -----------------------------VRKSYQRALLILHPDKLQQKGASANQKYMAEKVFELLQEAWDHFNTLGP-

General information: TITO was launched using: RESULT: Template: 3AG7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 74 -14108 -190.65 -335.90 target 2D structure prediction score : 0.83 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -190.65 2D Compatibility (Sec. Struct. Predict.) : 0.83 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.868

(partial model without unconserved sides chains): PDB file : Tito_3AG7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3AG7-query.scw PDB file : Tito_Scwrl_3AG7.pdb: