Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFNQVMLVGRLTKDPDLRYTSAGAAVAHVTLAVNRSFKNASGEI--EADYVNCTLWRKTAENTALYCQKGSLVGVSGRIQTRSYENEEGVNVYVTEVLADTVRFMDPKPREKAAD 2VW9 Chain:B ((1-106)) MFNKVIMVGRLTRNVELKYLPSGSAAATIGLATSRRFKKQDGTLGEEVCFIDARLFGRTAEIANQYLSKGSSVLIEGRLTYESWMDQTGKKNSRHTITADSLQFMD---------

General information: TITO was launched using: RESULT: Template: 2VW9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 420 -23652 -56.31 -227.42 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain B : 0.81 3D Compatibility (PKB) : -56.31 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.516

(partial model without unconserved sides chains): PDB file : Tito_2VW9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2VW9-query.scw PDB file : Tito_Scwrl_2VW9.pdb: