Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFNRLFRVCFLAALIMAFTLPNSVYAQKPIFKEVSVHDPSIIETNGTFYVFGSHLASAKSNDLMQWQQLTTSVSNDNPLIPNVYEELKETFEWAQS-DTLWAADVTQLADGKYYMYYNACRGDSPRSAMGVAVADNIEGPYKNKGIFLKSG----MEGTSSDGTPYDATKHPNVVDPHTFFDKDGKLWMVYGSYSGGIFILEMNPKTGFPLPGQGYGKKLLGGNHSRIEGPYVLYNPDTQYYYLYLSYGGLDATGGYNIRVARSKKPDGPYYDAEGNPMLDVRGKGGTFFDDRSIEPYGVKLMGSYTFETENEKGTGYVSPGHNSAYYDEKTGRSYLIFHTRFPGRGEEHEVRVHQLFMNKDGWPVAAPYRYAGETLKEVKQKDITGTYKLIQHGKDISADIKQTINIQLNKNHTISGEMTGTWRKTGKNTADITLAGKK---YNGVFLRQWDSVREKNVMTFSVLNTSGEAVWGSK 4KC7 Chain:C ((25-471)) ---------------------------QPTFRWAVVHDPSIIKVGNMYYVFGTHLQVAKS-DLMHWEQINTSAHDKNPIIPNINEELKETLSWARTRNDIWAPQVIQLSDGRYYMYYCASTFGSPRSAIGIAVSDDIEGPYKHYAVIVKSGQVYSVDGPSEDGTPYDSRKHPNALDPGVFYDKEGNLWMVYGSWFGGIYILKLDPNTGLPLPGQGYGKRLVGGNHSSMEGPYILYSPDTDYYYLFLSFGGLDYRGGYNIRVARSKNPNGPYYDPEGKSMENCMG------SKTVISNYGAKLVGNFILS-----AFGYVSPGHNSAY----TGKYFIFFHTRFPGRGETYQLRVHQLFLNEDGWFVMAPFPYGGETVSKLPNEEIVGEYQFINHGKEITDKIKQPVRIKLNSDGSITGAVEGRWERKEHYITLKIIEGNTTVIYKGVLLKQWHYS---WVTVFTALSNQGVSVWGIR

General information: TITO was launched using: RESULT: Template: 4KC7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 2730 26409 9.67 62.43 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain C : 0.84 3D Compatibility (PKB) : 9.67 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.637

(partial model without unconserved sides chains): PDB file : Tito_4KC7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4KC7-query.scw PDB file : Tito_Scwrl_4KC7.pdb: