Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLRTEKEKMAAGELYNSEDQQLLLERKHARQLIRQYNET-PEDDAVRTKLLKELLGSVGDQVTILPTFRCDYGYHIHIGDHTFVNFDCVILDVCEVRIGCHCLIAPGVHIYTAGHPLDPIERKSGKEFGKPVTIGDQVWIGGRAVINPGVTIGDNAVIASGSVVTKDVPANTVVGGNPARILKQL 1KRU Chain:C ((7-185)) ------ERIRAGKLFTDMCEGLPEKRLRGKTLMYEFNHSHPSEVEKRESLIKEMFATVGENAWVEPPVYFSYGSNIHIGRNFYANFNLTIVDDYTVTIGDNVLIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGSHVVINPGVTIGDNSVIGAGSIVTKDIPPNVVAAGVPCRVIREI

General information: TITO was launched using: RESULT: Template: 1KRU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 892 -50039 -56.10 -281.12 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain C : 0.82 3D Compatibility (PKB) : -56.10 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.667

(partial model without unconserved sides chains): PDB file : Tito_1KRU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1KRU-query.scw PDB file : Tito_Scwrl_1KRU.pdb: