Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKHITTVVIWKILRCLSLVFGVSILTFILLKQSPVDPVMASVNYDTSLTPVQYKAIAHHYGLDKPAPVQYFIWLKNFIQGHLGTSLVYRQPVIDIIRSRAGASFILMGLSWVLSGLIGFILGTLSAFHQGKLLDRIVRWFSYLQISVPTFWIGLIFLLIFSVQLGWFPIGISSPIGTLSQDITLADRIKHL-ILPVFTLSILGIANVTLHTRTKMMSVLSSEYVLFARARGETEWQIFKNHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGLGSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKV 4FYP Chain:A ((34-261)) GLSINY------PNCRSWHLGVETSNIINFDTVP-------------------------------------ANCKAYVEDYLITS---KQYQYDSKTVNKEAYFYAKGLALKNDTVNVWIFDL-----DDTLLSSIPYYAKYGYGTENTAP---------GAYWSWLESGESTP--GLPETLHLYENLLELGIEPIIISDRWKKLSEVTVENLKAVGVTKWKHLILKPNGSKLTQVVYKSK-VRNSLVKK--------GYNIVGNIGDQ-------------WADLVEDTP--------GRVFKLP-----NPLYYVPSLEHHHH-

General information: TITO was launched using: RESULT: Template: 4FYP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -117279 for 1800 contacts (-65.2/contact) + 2D Compatibility (PS) -23110 + (NN) 3602 + (LL) 8724 1D Compatibility (HY) -5200 + (ID) 2400 Total energy: -135663.0 ( -75.37 by residue) QMean score : 0.053

(partial model without unconserved sides chains): PDB file : Tito_4FYP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4FYP-query.scw PDB file : Tito_Scwrl_4FYP.pdb: