Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTTEYVAEILNELHNSAAY-ISNEEADQLADHILSSHQIFTAGAGRSGLMAKSFAMRLMHMGFNAHIVGEILTPPLAEGDLVIIGSGSGETKSLIHTAAKAKSLHGIVAALTINPESSIGKQADLIIRMPGSPKDQSNGSYKTIQPMGSLFEQTLLLFYDAVILKLMEKKGLDSETMFTHHANLE 1JEO Chain:A ((8-179)) ----DIVSNNILILKKFYTNDEWKNKLDSLIDRIIKAKKIFIFGVGRSGYIGRCFAMRLMHLGFKSYFVGETTTPSYEKDDLLILISGSGRTESVLTVAKKAKNINNNIIAIVCEC-GNVVEFADLTIPLEVKKSKY----LPM--G--TTFEETALIFLDLVIAEIMKRLNLDESEIIKRHCNL-

General information: TITO was launched using: RESULT: Template: 1JEO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 812 -124576 -153.42 -728.51 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -153.42 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.570

(partial model without unconserved sides chains): PDB file : Tito_1JEO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JEO-query.scw PDB file : Tito_Scwrl_1JEO.pdb: