Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKWSELSIHTTHEAVEPISNILHEAGASGVVIEDPLDLIKERENVYGEIYQLDPNDYPDEGVIVKAYLPVNSFLGETVDGIKETINNLLLYNIDLGRNHITISEVNEEEWATAWKKYYHPVKISEKFTIVPTWEEYTPVHTDELIIEMDPGMAFGTGTHPTTVLCIQALERFVQKGDKVIDVGTGSGILSIAAAMLEAESVHAYDLDPVAVESARLNLKLNKVSDIAQVKQNNLLDGIE-GEHDVIVANILAEVILRFTSQAYSLLKEGGHFITSGIIGHKKQEVKEALEQAGFTIVEILSMEDWVSIIAKK 3CJT Chain:I ((53-248)) -------------------------------------------------------------------------------------------------------EVGDEDWLEAWRRDLKPA-LAPPFVVLAPWHTW---EGAEIPLVIEPGMAFGTGHAETTRLALKALARHLRPGDKVLDLGTGSGVLAIAAEKLGGKAL-GVDIDPMVLPQAEANAKRNGVRP--RFLEGSLEAALPFGPFDLLVANLYAELHAALAPRYREALVPGGRALLTGILKDRAPLVREAMAGAGFRPLEEAAEGEWV------

General information: TITO was launched using: RESULT: Template: 3CJT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain I - contact count / total energy / energy per contact / energy per residue : 1032 -72255 -70.01 -370.54 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain I : 0.68 3D Compatibility (PKB) : -70.01 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.556

(partial model without unconserved sides chains): PDB file : Tito_3CJT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3CJT-query.scw PDB file : Tito_Scwrl_3CJT.pdb: