Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNYDHILIRFGEISTKGKNRKSFIERLKQNIRLVLKDYPNLKYFSNRDRMTITLNGEDPEALFPHLKQVFGIQSFSLAIKCDSRLDDIKATALKAIKDQYKPGDTFKVATKRAYKQFELDTNQMNAEIGGHILRNTEGLTVDVRNPDIPLRIEIREEATFLTIRDEKGAGGLPVGSAGKAMLMLSGGFDSPVAGFYAMKR-GLSVEAVHFFSPPYTSERAKQKVMDLAKCLSRFGGSMT-LHIVPFTKTQE-LI----QK-Q----IPENYTMTATRRLMLQIADRIREKRNGLAIITGESLGQVASQTLESMYAINAVTSTPILRPLIAMD---KTEIIEKSREIGTYETSIQPFEDCCTIFTPPSPKTRPKKEKIEHFESFVDFEPYIQEAVDNIETMTLYSEQEANDKFAELF 1KOR Chain:A ((2-180)) ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KIVLAYSGGLDTSIILKWLKETYRAEVIAFTADIGQG---EEVEEAREKALRT-----GASKAIALDLKEEFVRDFVFPMMRAGAVYEGYYLLGTSIARPLIAKHLVRIAEEEGAEAIAHGATGKG-NDQVRFELTAYALKPDIKVIAPWREWSFQGRKEMIAYAEAHGIPVP-----------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1KOR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 689 -6750 -9.80 -45.30 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.57 3D Compatibility (PKB) : -9.80 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.525

(partial model without unconserved sides chains): PDB file : Tito_1KOR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1KOR-query.scw PDB file : Tito_Scwrl_1KOR.pdb: