Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA 5A14 Chain:A ((3-292)) ----------ENFQKVEKIGEGTYGVVYKARN-KLTGEVVALKKIRLD--TEGVPSTAIREISLLKELN---HPNIVKLLDVIHT-----ENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFG---------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL----------------

General information: TITO was launched using: RESULT: Template: 5A14.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -162970 for 2065 contacts (-78.9/contact) + 2D Compatibility (PS) -28800 + (NN) -14854 + (LL) 2400 1D Compatibility (HY) -32800 + (ID) 7100 Total energy: -244124.0 ( -118.22 by residue) QMean score : 0.724

(partial model without unconserved sides chains): PDB file : Tito_5A14.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5A14-query.scw PDB file : Tito_Scwrl_5A14.pdb: