Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKIVVALGGNAL---GKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGK--VGTVIKK 2WE4 Chain:B ((4-310)) --KMVVALGGNAILSNDASAHAQQQALVQTSAYLVHLIKQGHRLIVSHGNGPQVGNLLLQ-QQAADSEKNPAMPLDTCVAMTQGSIGYWLSNALNQELNKAGIKKQVATVLTQVVVDPADEAFKNPTKPIGPFLTEAEAKEAM-QAGAIFKEDAGRGWRKVVPSPKPIDIHEAETINTLIKNDIITISCGGGGIPVVGQE---LKGVEAVIDKDFASEKLAELVDADALVILTGVDYVCINYGKPDEKQLTNVTVAELEEYKQAGHFAPGSMLPKIEAAIQFVESQPNKQAIITSLENL-GSMSGDEIVGTVVTK

General information: TITO was launched using: RESULT: Template: 2WE4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -148573 for 2511 contacts (-59.2/contact) + 2D Compatibility (PS) -32778 + (NN) -12099 + (LL) 312 1D Compatibility (HY) -27200 + (ID) 7650 Total energy: -227988.0 ( -90.80 by residue) QMean score : 0.603

(partial model without unconserved sides chains): PDB file : Tito_2WE4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2WE4-query.scw PDB file : Tito_Scwrl_2WE4.pdb: