Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKISITAPAKINLSLDALYKREDGYHEVEMVMTTIDLADRLYLERLDEDKIVLDVKAHF-IPEDRRNLIYQAALLLKKRFDVKMGVRITIDKHIPVSAGLAGGSSDAAAALKGLNVIWELGLSIEELAEISSEIGSDIAFCVYGGTALATGRGEKISALPNIPGCWIVLAKPSISVSTPTIYKELQVDNVEHPD-TQKMIESIKNGDLDGIFAATGNVLESVTLEKNPQVKRIKDRMLAFGAEAALMSGSGPTVFALIKQYSRAKRVYNGLRGFCEEVYMVRPWSEGENDTNINY 2V2V Chain:B ((5-246)) --IKVLSPAKINLGLWVLGRLPSGYHEILTLYQEIPFYDEIYIR-----EGVLRVETNIGIPQEE-NLVYKGLREFERITGIEINYSIFIQKNIPPGAGLGGGSSNLAVVLKKVNELLGSPLSEEELRELVGSISADAPFFLLGKSAIGRGKGEVLEPVETEISGKITLVIPQVSSSTGRVYSSLREEHFVTPEYAEEKIQRIISGEVEEI----ENVLGDIARELYPEINEVY-RFVEYLGFKPFVSGSGSTVY----------------------------------------

General information: TITO was launched using: RESULT: Template: 2V2V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -105408 for 2008 contacts (-52.5/contact) + 2D Compatibility (PS) -26019 + (NN) -7609 + (LL) 3548 1D Compatibility (HY) -20000 + (ID) 3950 Total energy: -159438.0 ( -79.40 by residue) QMean score : 0.373

(partial model without unconserved sides chains): PDB file : Tito_2V2V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2V2V-query.scw PDB file : Tito_Scwrl_2V2V.pdb: