Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKDRYILAVESSCDETSVAILKNDKELLANIIASQVESHKRFGGVVPEVASRHHVEVVTTCFEDALQEAGIVASDLDAVAVTYGPGLVGALLVGMAAAKAFAWANKLPLIPVNHMAGHLMAARDVKELQYPLLALLVSGGHTELVYVSGPGDYKIVGETRDDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMIKEDHLEFSFSGLKSAFINLHHNAEQKGEALVLEDLCASFQAAVLDILLAKTQKALLKYPVKTLVVAGGVAANQGLRE--RLATDISPDIDVVIPPLRLCGDNAGMIALAAAIEFEKENFASLKLNAKPSLAFEGL 2IVO Chain:C ((4-291)) ------LGIEGTAHTLGIGIVSEDK-VLANVFDTLTTEK---GGIHPKEAAEHHARLMKPLLRKALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITK-MFGVKDP-VGLYVSGGNTQVLALEG-GRYRVFGETLDIGIGNAIDVFARELGLGFPGGPKVEKLAEKGEKYIELPYAV---KGMDLSFSGLLTEAIRKYRSGKYR-----VEDLAYSFQETAFAALVEVTERAVAHTEKDEVVLVGGVAANNRLREMLRIMTE-DRGIKFFVPPYDLCRDNGAMIAYTGLRMYKAGISFRLEETIVKQKFRTDE

General information: TITO was launched using: RESULT: Template: 2IVO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -202255 for 2490 contacts (-81.2/contact) + 2D Compatibility (PS) -31653 + (NN) -19588 + (LL) 1972 1D Compatibility (HY) -22400 + (ID) 5150 Total energy: -279074.0 ( -112.08 by residue) QMean score : 0.543

(partial model without unconserved sides chains): PDB file : Tito_2IVO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2IVO-query.scw PDB file : Tito_Scwrl_2IVO.pdb: