Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTTKVFSVLSLSVAAFMMTACQSNHSTKKADMSPDKVEQKTKFKNISLSSNKLLAKENTMSVLWYQNSAEAKALYLQGYNVAKMKLDDWLQKPSEKPYSIILDLDETVLDNSPYQAKNIKDGSSFTPESWDKWVQKKSAKAVAGAKAFLKYANEKGIKIYYVSDRTDAQVDATKENLEKEGIPVQGKDHLLFLKKGMKSKESRRQAVQKDTNLIMLFGDNLVDFA-DFSKSSSTDREQLLTKLQSEFGSKFIVFPNPMYGSWESAIYQGKHLDV-QKQLKERQKMLHSYD 2I33 Chain:A ((14-250)) ----------------------------------------------------VKLTDQQLMADLWYQTAGEMKALYYQGYNTGQLKLDAALAKGTEKKPAIVLDLDETVLDNSPHQAMSVKTGKGY-PYKWDDWINKAEAEALPGSIDFLKYTESKGVDIYYISNRKTNQLDATIKNLERVGAPQATKEHILLQDPKEKGKEKRRELVSQTHDIVLFFGDNLSDFTGFDG-KSVKDRNQAVTDSKAQFGEKFIIFPNPMYGDWEGALYDYNFKKSDAEKDKIRHDNLKSFD

General information: TITO was launched using: RESULT: Template: 2I33.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -21299 for 1824 contacts (-11.7/contact) + 2D Compatibility (PS) -25860 + (NN) -16911 + (LL) 3852 1D Compatibility (HY) -16000 + (ID) 5350 Total energy: -81568.0 ( -44.72 by residue) QMean score : 0.499

(partial model without unconserved sides chains): PDB file : Tito_2I33.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2I33-query.scw PDB file : Tito_Scwrl_2I33.pdb: