Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNQLHRRMGTFSLMMVGLGSMIGSGWLFGAWRAAQIAGPAAIISWVIGMVVILFIALS--YSELGSMFPEAGGMVKYTQYSHGSFIGFIAGWANWIAIVSVIPVEAVASVQYMSSWPWEWAKWTSGLVKNGTLTGEGLAFASVLLLIYFLLNYWTVNLFSKANSLITIFKIIIPGLTIGALLFVGFHGENFTGGQSIAPNGWASVLTAVATSGIVFAFNGFQSPINMAGEAKNPGKSIPIAVVGSLFVATVIYVLLQIAFIGAVNPSDIAHGWSHLNFNSPFADLAIALNINWLVIVLYADAFVSPSGTGITYTATTSRMIYGMEKNKYMPSIFGKLHPIYGVPRQAMFFNLIVSFIFLFLFRGWGVLAEIISVA--TLISYITGPITVMTLRRTGKDLYRPLRLKGLNVIAPLGFIFASLVLYWARWPLTGQVLFIILIGLPIYFYYQAKAKWKGFGRNFKAGVWMVFYLLAMMVISYLGSDKFGGLNVIHYGWDMVLIAMVSLVFYVWALKSGYQTEYLKDAKEINSQLLNGQSEAAAGKE 1ZY7 Chain:A ((8-402)) -----SRQPIPS-------------------EGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTD-----------VKDAKVISVSTGTKCINGEYMSD---------RGLALNDC----HAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERG---------GFRL----------------------KENVQFHLYISTSP---CGDARIFKAR------GQLRTKI-----------------ESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGI---------------QGSLLSIF--VEPIY-----------FSSIIL-----GSLYHGDHLSRAMYQRISNIEDLPPLYTLNK-------PLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINAT----------TGKDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLT----------

General information: TITO was launched using: RESULT: Template: 1ZY7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2193 -229472 -104.64 -613.56 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.57 3D Compatibility (PKB) : -104.64 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.216

(partial model without unconserved sides chains): PDB file : Tito_1ZY7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ZY7-query.scw PDB file : Tito_Scwrl_1ZY7.pdb: