Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTQMRFTEEDFNTFTIEGLDARMEVLKETVRPKLTAL----GEHFAPTLSALTGDEMFPHVAKHARRSVNPPADSW-VAFANSKRGYKKLPHFQIGLWESHVFVWFAI------IYESPIKEEYGK----LLEVNQETITKNIPDSFVWSADHTKPG--VHKQSEMDKEQLKTLFERLQTVKKAELLCGIQLQKEEVLNMNNQEFLQRIDDAFKQLAFL-----YRLTQKVTQA-------- 1QB7 Chain:A ((1-236)) ----PFKEVSPNSFLLDDSHALSQLLKKSYRWYSPVFSPRNVPRFADVSSITESPETLKAIRDFLVQRYRAMSPAPTHILGFDARGFLFGPMIAVELEIPFVLMRKADKNAGLLIRSEPYEKEYKEAAPEVMTIRYGSIGKG--SRVVLIDDVLATGGTALSGLQLVEASDAVVVEMVSILSIPFLKAAEKIHSTANSRYKDIKFISLLSDDALTEENCGDSKNYTGPRVLSCGDVLAEHPH

General information: TITO was launched using: RESULT: Template: 1QB7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1005 -87411 -86.98 -424.32 target 2D structure prediction score : 0.35 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -86.98 2D Compatibility (Sec. Struct. Predict.) : 0.35 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.077

(partial model without unconserved sides chains): PDB file : Tito_1QB7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QB7-query.scw PDB file : Tito_Scwrl_1QB7.pdb: