Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTICVFAGSNPGGNEAYKRKAAELGVYMAEQGIGLVYGGSRVGLMGTIADAIMENGGTAIGVMPSGLFSGEVVHQNLTELIEVNGMHERKAKMSELADGFISMPGGFGTYEELFEVLCWAQIGIHQKPIGLYNVNGYFEPMMKMVKYSIQEGFSNESHL-KLIHSSSRPDELIEQMQNYSYPILEKKWTEI 3SBX Chain:G ((47-184)) -----------------------------------LVWGGGHVSAMGAVSSAARAHGGWTVGVIPKMLVHRELADHDADELVVTETMWERKQVMEDRANAFITLPGGVGTLDELLDVWTEGYLGMHDKSIVVLDPWGHFDGLRAWLSELADTGYVSRTAMERLIVVDNLDDAL-------------------

General information: TITO was launched using: RESULT: Template: 3SBX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain G - contact count / total energy / energy per contact / energy per residue : 511 -64896 -127.00 -473.69 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain G : 0.71 3D Compatibility (PKB) : -127.00 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.367

(partial model without unconserved sides chains): PDB file : Tito_3SBX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3SBX-query.scw PDB file : Tito_Scwrl_3SBX.pdb: