Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGKLLTMAMPKGRIFEEAAGLLRQAGYRLPEEFEDSRKLIIDVPEENLRFILAKPMDVTTYVEHGVADVGIAGKDVMLEEE-RDVYEVLDLNISKCHLAVAGLPNTDWSGVA--PRIATKYPNVASSYFREQGEQVEIIKLNGSIELAPLIGLADRIVDIVSTGQTLKENGLVETEHICDITSRFIVNPVSYRMKDDVIDEMASRLSLVVEGETAK 1Z7M Chain:F ((1-202)) ---MIKIAITKGRIQKQVTKLLENADYDVEPILNLGRELQIKT-KDDLQIIFGKPNDVITFLEHGIVDIGFVGKDTLDENDFDDYYELLYLKIGQCIFALASYPDFSNK---RHKRIASKYPRVTKKYFAQKQEDIEIIKLE-SVELGPVVGLADAIVDIVETGNTLSANGLEVIEKISDISTRMIVNKSSFKFKKDKIIEMVERL----------

General information: TITO was launched using: RESULT: Template: 1Z7M.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain F - contact count / total energy / energy per contact / energy per residue : 958 -40680 -42.46 -208.62 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain F : 0.83 3D Compatibility (PKB) : -42.46 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.462

(partial model without unconserved sides chains): PDB file : Tito_1Z7M.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Z7M-query.scw PDB file : Tito_Scwrl_1Z7M.pdb: