Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQDFSSLLLKLQEYWKDQGCLVIQPYDIPAGAGTFHPATLLRSLDKKPWNVAYVAPSRRPTDGRYGENPN--RLGSYYQFQ--VVIKPSPS-----NIQELYLKSLEVLGINLNEHDIRFV-EDNWESPTLGAWGLGWEVWLDGM--EVTQFTYF---QQ--------------VGGIPCSPIPVEITYGLERLTMYVQKVENILEIEWAKKDNESVRYAQVHLESEYEFSKYHFEVASVERLLEMFKNAQAEALHCLENKLPLPAYDLVMLCSHFFNILDARKAISVAERQNYILQIRDLAKGCAVLYKEQEEEREERLKNALTKA 3IKL Chain:A ((202-349)) --------------------------------------------KRLPYGLAQIGVCFHP----------VKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPS----NFSSSDCQDEEGRKGN--KLYYNFPWGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKNV------

General information: TITO was launched using: RESULT: Template: 3IKL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -34808 for 665 contacts (-52.3/contact) + 2D Compatibility (PS) -12110 + (NN) -3490 + (LL) 3532 1D Compatibility (HY) -1600 + (ID) 650 Total energy: -49126.0 ( -73.87 by residue) QMean score : 0.330

(partial model without unconserved sides chains): PDB file : Tito_3IKL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3IKL-query.scw PDB file : Tito_Scwrl_3IKL.pdb: