Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----------------------------MKKRI-ILLLA----VIIAAAAAGVAFYVAKDKGHEKAADVSVN--------TESGDELLVSI-TDTDLLTKYYENDKVIHEEKLTSYPAFALDQKQQVLYYTGNNEQNEMRLFKLDLKSHKKTMLYKGAESADSLFLSKDRSTIYFRLGKA-DESNFRIAAFDLKTKKYKNLYPAANDQDDTVSSFFYNQKNDSFALLHYSVEEDYKKTDEANEKGIDPEPTTIH-FAEGRQNKFNELKSLNQFISDIAVSDDDKRILFTSYTQKGTEQTASIQMLNADTKKYESI-ISNQKSF------------------KLLIDAQPQFSKDGKNIYFLAEAKGAKKLKDETGREAKVRT---IYSYSLE-NKTFKKVWENPNGIINSFFVIN---------- 1L0Q Chain:A ((1-391)) STFAYIANSESDNISVIDVTSNKVTATIPVGSNPMGAVISPDGTKVYVANAHSNDVSIIDTATNNVIATVPAGSSPQGVAVSPDGKQVYVTNMASSTLSVIDTTSNTVAGTVKTGKSPLGLALSPDGKKLYVTNNGDKTVSVINTV--TKAVINTVSVGRSPKGIAVTPDGTKVYVANFDSMS-----ISVIDTVTNSVIDTVKV----EAAPSGIAVNPEGTKAYVTNV-----------------DKYFNTVSMIDTGTNKITARIPV-GPDPAGIAVTPDGKKVYVALSFN-------TVSVIDTATNTITATMAVGKNPYASGQFIGSIPVQPVYPSADFKSNITSGYIFLSEPVQFTDLSKDATEWKWDFGDGSSSKKQNPTHTYSETGIYTVRLTVSNSNGTDSQISTVNVVLKGSPTPS

General information: TITO was launched using: RESULT: Template: 1L0Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1636 -104088 -63.62 -333.61 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -63.62 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.380

(partial model without unconserved sides chains): PDB file : Tito_1L0Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1L0Q-query.scw PDB file : Tito_Scwrl_1L0Q.pdb: