Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MILYTVMPQEIVFAEQNQETSAHEQIEYKGVPL--LVEMKGNEAEV-----------IQIMSTNPMHFLHPDISPG---QKLKLNV--------- 1EHX Chain:A ((1-94)) MQDPTINPTSISA-KAGSFADTKITLTPNGNTFNGISELQSSQYTKGTNEVTLLASYLNTLPENTTKTLTFDFGVGTKNPKLTITVLPKDIPGLE

General information: TITO was launched using: RESULT: Template: 1EHX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 274 -19526 -71.26 -282.99 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -71.26 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.115

(partial model without unconserved sides chains): PDB file : Tito_1EHX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1EHX-query.scw PDB file : Tito_Scwrl_1EHX.pdb: