Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNWMEFISSIVKSIIWPVAIIILVFKLKQPVSNLISTLAKIKYKDWEFEFTIDQKLDKISFQLNKENQYGTDDQNLKDSLNLESNSEITEETHSHYNEKTSIKGDNDLLLKMEMIRLYGAVKNLYEKVSEKDDAADKSQG-----IGMLYMVDYLK---RHKILNDSFAESLLDIMNIVHDLEKSHIS----------QSYIMNKFFWNVDKSVKRLMEITSNYVAENTAGETSN 5FIK Chain:W ((10-226)) ------ITPVILGLPLVTLIVLFPSLLFPTSNRLVS-NRFVTLQQWMLQLVSKQMMSI-------HNSKGQTWTLMLMSLILFIGSTNLLGLLPHSFTPT---TQLSMNLGMAIPLWAGAVITGFRNKTKASLAHFLPQGTPTPLIPMLVIIETISLFIQPMALAVRLTANITAGHLLIHLIGGATLALMSISTTTALITFTILILLTILEFAVAMIQAYVFTLLVSLYLHDNT-

General information: TITO was launched using: RESULT: Template: 5FIK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain W - contact count / total energy / energy per contact / energy per residue : 703 -23999 -34.14 -120.60 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain W : 0.60 3D Compatibility (PKB) : -34.14 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.143

(partial model without unconserved sides chains): PDB file : Tito_5FIK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5FIK-query.scw PDB file : Tito_Scwrl_5FIK.pdb: