Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MANYTLAPEDEYDVLIEGELESDEAEQCDKYDAQALSAQLVPSLCSAVFVIGVLDNLLVVLILVKYKGLKRVENIYLLNLAVSNLCFLLT--LPFWAHA-------GGDPMCKILIGLYFVGLYSETFFNCLLTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEFVVYKPQM-EDQKYKCAFSRTPFLPADETFWKHFLTLKMNISVLVLPLFIFTFLYVQMRKTLR-F----------------------REQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCKSSYNLDKSVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV 2Z73 Chain:A ((28-335)) -------------------------------QVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISCFLKKWIFGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASK-KMSHRRAFIMIIFVWLWSVLWAIGPIFGWGAYTLEGVLCNCSFDYIS-----RDSTTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKRLNAKELRKAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQFGPL--------EWVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETEDDKDAETEIPAGE-

General information: TITO was launched using: RESULT: Template: 2Z73.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -238162 for 2227 contacts (-106.9/contact) + 2D Compatibility (PS) -28039 + (NN) -10467 + (LL) 2836 1D Compatibility (HY) -20400 + (ID) 2550 Total energy: -296782.0 ( -133.27 by residue) QMean score : 0.291

(partial model without unconserved sides chains): PDB file : Tito_2Z73.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Z73-query.scw PDB file : Tito_Scwrl_2Z73.pdb: