Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKCIKTLFLSIILVVMGGWYHSAHASDSLSKSPENWMSKLDESKHLTEINMPGSHDSGSFTLTDPVKSVWAKTQGKDYLTQMKSGVRFFDIRGRASADNMISVHHGMVYLHHELGKFLDDAKYYLSAYPNETIVMSMKKDYDSDSKVTKTFEEIFREYYYNNPQYQNLFYTGSNANPTLKETKGKIVLFNRMGGTYIKSGYGADTSGIQWADNATFETKINNGSLNLKVQDEYKDYYDKKVEAVKNLLAKAKTDSNKDN-VYVNFLSVASGGSAFNSTYNYASHINPEIAKTIKENGKARTGWLIVDYAGYPWPGYDDIVSEIIDSNK 3EA3 Chain:B ((13-293)) ------------------------------------WMQPIPDNIPLARISIPGTHDSGTFKLQNPIKQVWGMTQEYDFRYQMDHGARIFDIRGRLTDDNTIVLHHGPLYLYVTLHEFINEAKQFLKDNPSETIIMSLKKEYEDMKGAEGSFSSTFEKNYFVDP-----IFLKTEGNIKLGDARGKIVLLKRYSGSNESGGY----NNFYWPDNETFTTTVNQ-NVNVTVQDKYKVNYDEKVKSIKDTMDETMNNSEDLNHLYINFTSLSSGGTAWNSPSSSASSINPEIANDIKQKNPTRVGWVIQDYINEKWSPL--LYQEVIRANK

General information: TITO was launched using: RESULT: Template: 3EA3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -73432 for 2394 contacts (-30.7/contact) + 2D Compatibility (PS) -30546 + (NN) -15226 + (LL) 2584 1D Compatibility (HY) -22800 + (ID) 5850 Total energy: -145270.0 ( -60.68 by residue) QMean score : 0.439

(partial model without unconserved sides chains): PDB file : Tito_3EA3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3EA3-query.scw PDB file : Tito_Scwrl_3EA3.pdb: