Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSKLQDVIVQEMKVKKRIDSAEEIMELKQFIKNYVQSHSFIKSLVLGISGGQDSTLVGKLVQMSVNELREEGIDCTFIAVKLPYGVQKDADEVDQALRFIEPDEIVTVNIKPAVDQSVQSLKEA-GIVLTDFQKGNEKARERMKVQFSIASNRQGIVVGTDHSAENITGFYTKYGDGAADIAPIFGLNKRQGRQLLAYLGAPKELYEKTPTADLEDDKPQLPDEDALGVTYEAIDNYLEGKPVTPEEQKVIENHYIRNAHKRELAYTRYTWPKS 4Q16 Chain:D ((8-275)) LSPLRSHIIRELHVQPDIDPGAEVERRVAFLCDYLQS-TPTKGFVLGISGGQDSTLAGRLCQLAVERRRSQGHGATFLAVRLPYGVQADEADAQQALDFIQADREVTVNIKEAADASVAAAQAALGSEVRDFVRGNVKARERMVAQYALAGQENLLVVGTDHAAEALTGFYTKYGDGGVDLTPLSGLTKRQGAQLLAHLGAPEGTWRKVPTAD----RPGLPDEVALGVTYAQIDAYLEGREVSDEAAARLERLFLNSRHKRALPVTPF-----

General information: TITO was launched using: RESULT: Template: 4Q16.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -48050 for 2130 contacts (-22.6/contact) + 2D Compatibility (PS) -28778 + (NN) -15150 + (LL) 276 1D Compatibility (HY) -18800 + (ID) 6800 Total energy: -117302.0 ( -55.07 by residue) QMean score : 0.417

(partial model without unconserved sides chains): PDB file : Tito_4Q16.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4Q16-query.scw PDB file : Tito_Scwrl_4Q16.pdb: