Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLSELLSAYSIETEFSNDFEVHALAELDKATPNDISYIDQVCYLKLLKDSKAGAVFIRKKESSKVPKSMQALIVDNPHLAFAKVSHAFKIPFFKNPQSVNE----------PKHFEKVTIMPNVVIGEGVEIGENSLIYPGVVIADGVKIGKNCILYPRVILYQNTILEDNVIIHAGSVIGGDGFGYAHTALGEHVKIEHVGIVRIQKNVEIGANTAIDRAVFGETLIKEGVKIDNLVQIGHNCVLGEHSIVVSQVGLSGSTTTGRNVVFGGQVGIGGHLHVGEFTQIGGKSAVGKDLPPNTNFAGAIPAMEIHEWHHFLAHLRTNFRKQQKTSLLQKAKGFFKS 3EH0 Chain:A ((4-318)) IRLADLAQQLDAELHGDGDIVITGVASMQSAQTGHITFMVNPKYREHLGLCQASAVVMTQDDLPFAKSA--ALVVKNPYLTYARMAQILD----TTPQPAQNIAPSAVIDATAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTIYHEIQIGQNCLIQSGTVVGADGFGYANDR-GNWVKIPQIGRVIIGDRVEIGACTTIDRGALDDTIIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGHMEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKSLERKVNQQD-

General information: TITO was launched using: RESULT: Template: 3EH0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -247120 for 2428 contacts (-101.8/contact) + 2D Compatibility (PS) -33587 + (NN) -12722 + (LL) 876 1D Compatibility (HY) -20800 + (ID) 4850 Total energy: -318203.0 ( -131.06 by residue) QMean score : 0.368

(partial model without unconserved sides chains): PDB file : Tito_3EH0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3EH0-query.scw PDB file : Tito_Scwrl_3EH0.pdb: