Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVAISGGGTGGHVYPALALIRELKKSHPEAEFLYIGTEKGLEAGIVKREGIPFEAIEITGFKR---------SLS---------LENIKT----VMRF-LSGAKKSKQILRDFKPDVVIGTGGYVCGPVVYAAAKLKIPTLIHEQNSVAGL-----TNKFLSRY--------T---DKVAICFEEVSDSFAS-----EKIVFTGNPRASEVVGVDSEGALEAYGLVSGKPTVLVFGGSRGARGVN-EAVEAVLPEWNNRDFQLLYVTGDVHYEKIKDSLAELNLGNHISVQPFIYDMPKILNAVTLVVSRAGATTLAELTALGVPSILIPSPYVTANHQENNARA--LEKNNAAIVITEAELKNTDLMATVDSILNDEAKLNSMKLSAKQMGRPDAAAKLVEAVLSIMK 3OTI Chain:A ((21-396)) MRVLFVSSPGIGHLFPLIQLAWGFRTAG--HDVLIAVAEHA---DRAAAAGLEVVDVAPDYSAVKVFEQVAKDNPRFAETVATRPAIDLEEWGVQIAAVNRPLVDGTMALVDDYRPDLVVYEQGAT--VGLLAADRAGVPAVQRNQSAWRTRGMHRSIASFLTDLMDKHQVSLPEPVATIESFPPSLLLEAEPEGWFMRWVPYGGGAVLGDRLP----------PVPARPEVAITMGT-IELQAFGIGAVEPIIAAAGEVDADFV-LALGDLDIS---PLG--TLPRNVRAVGWTP-LHTLLRTCTAVVHHGGGGTVMTAIDAGIPQLLAPDPR----DQFQHTAREAVSRRGIGLVSTSDKV---D-ADLLRRLIGDESLRTAAREVREEMVALPTPAETVRRIVERI-

General information: TITO was launched using: RESULT: Template: 3OTI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -164191 for 2811 contacts (-58.4/contact) + 2D Compatibility (PS) -35930 + (NN) -16788 + (LL) 1996 1D Compatibility (HY) -12000 + (ID) 2400 Total energy: -229313.0 ( -81.58 by residue) QMean score : 0.450

(partial model without unconserved sides chains): PDB file : Tito_3OTI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3OTI-query.scw PDB file : Tito_Scwrl_3OTI.pdb: