Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKKETAWMKRK------QLLYTEERKWEYGTIL--IEDGICLIENGEGDILLADSLQHSPIW--------IHHKGKWEQAGFQDKLVLACGAENISLSGGERIRYEKSVKRPLMALLDSLDDETFLAFLQHLHSFGLSVFDCVFSYNKGVFSNTSAGQGVSFYHFSNDTAQCAMQHHYNYSSEGTGDRFEWTASNGKRSIMYTAVQRGRK 4MT5 Chain:A ((0-183)) ---MQTAYVKYVDDTTGETLRQDDLHGYTDETIPYSTAEGIKKYE-GDGYVLVSDGFKPGTKFGVGTPTYEVHFKHGMTHTDATDK-----NAEQKTVT--ETIHYVDENNQTV--QPDSTTAVTFKRGYTTDNVTGK-----VVSYDPWTVDGNQADS----KTFAAVPSPAVEGYTPNHQQIN-----EFTVTPDSKDIVKTVVYVGDP

General information: TITO was launched using: RESULT: Template: 4MT5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 655 -12127 -18.51 -72.18 target 2D structure prediction score : 0.33 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -18.51 2D Compatibility (Sec. Struct. Predict.) : 0.33 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.063

(partial model without unconserved sides chains): PDB file : Tito_4MT5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MT5-query.scw PDB file : Tito_Scwrl_4MT5.pdb: