Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MISLQSDQLLEATVGQFMIEADKVAHVQVGNNLEHALLVLTKTGYTAIPVLDPSYRLHGLIGTNMIMNSIFGLERIEFEKLDQITVEEVMLTDIPRLHINDPIMKGFGMVINNGF--VCVENDEQVFEGIFTRRVVLKELNKHIRSLNK 1Y5H Chain:A ((2-124)) -----------TTARDIMN--AGVTCVGEHETLTAAAQYMREHDIGALPICGDDDRLHGMLTDRDIVIKGLAAGL----DPNTATAGELARDSIYYVDANASIQEMLNVMEEHQVRRVPVIS-EHRLVGIVTEADIARHLP--------

General information: TITO was launched using: RESULT: Template: 1Y5H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 560 -91963 -164.22 -760.02 target 2D structure prediction score : 0.36 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -164.22 2D Compatibility (Sec. Struct. Predict.) : 0.36 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.346

(partial model without unconserved sides chains): PDB file : Tito_1Y5H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Y5H-query.scw PDB file : Tito_Scwrl_1Y5H.pdb: