Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MERFEITKTPINTENIIKKVEKREAGAITTFIGTVREWT-NGKRTVRLEYEAYEPMAVQMLAQIGAEIEEKWEGASAAITHRIGVLDIGEAAVVIAVSSPHRKAAYEANEYAIERIKQIVPIWKKEIWEDGE-QWIGDQLETTAYPNGKPDLSEGEQHD 2OMD Chain:B ((30-142)) -----------------------DCGAQVLFLGIPRNAPEDGGNIEALEYEAYPEMAIKEMEKIRQETIEKFGVKEVFIHHRLGLVKIGEPSFLVLAVGGHREETFKACRYAVDETKKRVPIWKKEIFKEGKGEWV-----------------------

General information: TITO was launched using: RESULT: Template: 2OMD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 470 -43161 -91.83 -388.83 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain B : 0.78 3D Compatibility (PKB) : -91.83 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.540

(partial model without unconserved sides chains): PDB file : Tito_2OMD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OMD-query.scw PDB file : Tito_Scwrl_2OMD.pdb: