Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAQNNENALPDITKSITLEAPIQKVWETVSTSEGIAKWFMPNDFQLKEGQEFHLQ-SPFGPSPCKVLAVQAPTELSFEWDTE--------GWVVTFQLEDLGEKTGFTLIHSGWKEPNEVIGKANEKSSVVRGKMDGGWTGIVNERLRKAVEE 3Q63 Chain:A ((9-140)) ---------RTVVVERQISHPPEKLWRALTQPHLIEEWLMKNDFKPAVGHRFNISADWGGVLDCEVLAVEPNKTLSYTWNLAHQDPAFDLRSVVTFTLTPTPTGTHLRMEQSGFRPDQR----------RAYGGAKMGWPQ-FFEKLEQLLD-

General information: TITO was launched using: RESULT: Template: 3Q63.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 522 10511 20.14 85.45 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : 20.14 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.534

(partial model without unconserved sides chains): PDB file : Tito_3Q63.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3Q63-query.scw PDB file : Tito_Scwrl_3Q63.pdb: