Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKRFSTAYLLLGILCSAAVFLIGAPSRALGAEVEHYEPLQVHVQ--------------LEKVYLDGDVSIEHKHEKVFSMDDFWAAYAGWTLVEQK------KGYVLFRK-----QMDDISPLSKVNGYIGVSDNGVISTFHGRPEPASEPIQSFFQIDLERLESHMQKNLL----KGIPFRTKAEFEDVIEHM-------KTYSG------ 3C9A Chain:A ((10-217)) ----DRDVRILYQVGDSEEDLPVCAPNAVCSKIDLYETPWIERQCRCPDGRTCPSSLGVEDGHTIADKTRHYKMCQPVHKLPVCKHFRDYTWTLTTAAELNVTEQIVHCRCPRNSVTYLTKREPIGNDSPGYRYLFACSPLTRLRCQRKQPCKLFTVRKRQEFLDEVNINSLCQCPKGHRCPSHHTQSGVIAGESFLEDNIQTYSGYCMAND

General information: TITO was launched using: RESULT: Template: 3C9A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 699 4864 6.96 29.30 target 2D structure prediction score : 0.41 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : 6.96 2D Compatibility (Sec. Struct. Predict.) : 0.41 1D Compatibility (Hydrophobicity) : 0.60 QMean score : -0.039

(partial model without unconserved sides chains): PDB file : Tito_3C9A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3C9A-query.scw PDB file : Tito_Scwrl_3C9A.pdb: