Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIIMKEAIIATHNPGKVKEFKEILEPRGYDVKSLAEIGFTEEIEETGHTFEENAIMKAEAVAKAVNKMVIADDSGLSIDNLGGRPGVYSARYAGEQKDDQANIEKVLSELKGIEKEQRTARFRCALAVSIPGEETKTVEGHVEGYIAEEPRGE-YGFGYDPIFIVKDKDKTMAELTSDEKNKISHRADALKKLSKLLEA-- 1B78 Chain:A ((10-193)) -----KIYFATGNPNKIKEANIILK----DLKDVEIEQIKISYPEIQGTLEEVAEFGAKWVYNILKKPVIVEDSGFFVEALNGFPGTYSKFVQETI-----GNEGILKLLEG--KDNRNAYFKTVIGYCDE-NGVRLFKGIVKGRVSEEIRSKGYGFAYDSIFIPEEEERTFAEMTTEEKSQISHRKKAFEEFKKFLLDRI

General information: TITO was launched using: RESULT: Template: 1B78.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 913 -44872 -49.15 -247.91 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -49.15 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.478

(partial model without unconserved sides chains): PDB file : Tito_1B78.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1B78-query.scw PDB file : Tito_Scwrl_1B78.pdb: