Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDMKHTLLEALGIEIVENTAERCVAVMPVDHRTVQPFGYLHGGASVALAETAASAGAQNLIDHTTQACVGLEINANHLKSVKEGTVKAIAEPVHIGRTTIVYHIHIYDEQERLICISRCTLAVIKK 2B6E Chain:A ((24-137)) ----------LGIEISAFGEDWIEATMPVDHRTMQPFGVLHGGVSVALAETIGSL-AGSLCLEEGKTVVGLDINANHLRPVRSGKVTARATPINLGRNIQVWQIDIRTEENKLCCVSRLTLSVIN-

General information: TITO was launched using: RESULT: Template: 2B6E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 565 -88418 -156.49 -775.60 target 2D structure prediction score : 0.45 Monomeric hydrophicity matching model chain A : 0.81 3D Compatibility (PKB) : -156.49 2D Compatibility (Sec. Struct. Predict.) : 0.45 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.487

(partial model without unconserved sides chains): PDB file : Tito_2B6E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2B6E-query.scw PDB file : Tito_Scwrl_2B6E.pdb: