Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMKPVMLSVYGAENVCASCVNMPTAKDTYEWLEAALKRKYPNQPFEMQYIDIHEPPDNEHAKELAEKIRNDEYFYPLVLVEDKIVGEGNPKLKDVYEEMEKHGYTENR 1XG8 Chain:A ((-8-102)) -----AVVVYGADVICASCVNAPTSKDIYDWLQPLLKRKYPNISFKYTYIDITKDL-TDHDLQFIERIEQDELFYPLITMNDEYVADGYIQTKQITRFIDQKLVNE--

General information: TITO was launched using: RESULT: Template: 1XG8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 408 22123 54.22 221.23 target 2D structure prediction score : 0.23 Monomeric hydrophicity matching model chain A : 0.84 3D Compatibility (PKB) : 54.22 2D Compatibility (Sec. Struct. Predict.) : 0.23 1D Compatibility (Hydrophobicity) : 0.84 QMean score : -0.096

(partial model without unconserved sides chains): PDB file : Tito_1XG8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XG8-query.scw PDB file : Tito_Scwrl_1XG8.pdb: