Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSHTDLTPCTRVLASSGTVPIAEELLARVLEPYSCKGCRYLIDAQYSATEDSVLAYGNFTIGESAYIRSTGHFNAVELILCFNQLAYSAFAPAVLNEEIRVLRGWSIDDY-CQHQLSSMLIR-KASSRFRKPLNPQKFSARLLCRDLQVI-ERTWRYLKVPCVIEFWDENGGAA-SGEIELAAL-NIP----------- 1VK9 Chain:A ((2-148)) GSDKIHHHHHHV---------EKNLLRSALKIFEKKDL-------------SLLAYSGRSIFES---KDSGLKPVVELFKRFDNL-----------------EGSLVIDKMVGKAAASFLLKMK----------PDHIHAKVISKPALKLMNEYGQSFSYDEKIPFVLGKDGKSMCPFEKLVLEMDDPEEIIRIVLSKF

General information: TITO was launched using: RESULT: Template: 1VK9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -58734 for 943 contacts (-62.3/contact) + 2D Compatibility (PS) -13931 + (NN) -3298 + (LL) 4128 1D Compatibility (HY) -3200 + (ID) 1550 Total energy: -76585.0 ( -81.21 by residue) QMean score : 0.197

(partial model without unconserved sides chains): PDB file : Tito_1VK9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VK9-query.scw PDB file : Tito_Scwrl_1VK9.pdb: