Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIVLQAYIKVKPEKREEFLSEAQSLVQHS-RAEEGNAQYDLFEKVGEENTFVMLEKWKDEAAMKFHNETAHFQGFVAKGKELLSAPLDVVRTELSE 3BM7 Chain:A ((20-115)) MIGVVATLKVQPAKAAEFEKVFLDLAAKVKANEPGCLVYQLTRSKTEEGVYKVLELYASMDALKHHGGTDYFKAAGAAMGPTMAGAPVIEYLDAVE

General information: TITO was launched using: RESULT: Template: 3BM7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 358 -28098 -78.49 -295.77 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -78.49 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.513

(partial model without unconserved sides chains): PDB file : Tito_3BM7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3BM7-query.scw PDB file : Tito_Scwrl_3BM7.pdb: