Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEYQYPMNEDWTTEEAVDVIAFFQQVELAYEKGADREELLKAYRRFKEIVPGKAEEKKLCGEFEEQSTYSPYRTVKQARES-DHAKIKM 2OY9 Chain:A ((6-89)) ---TLPISLDWSTEEVIDVVHFFQAIEQAYDQGIAREDLLGKYRRFKEIVPSKSEEKQLFRAYEQENDVSCYQTIKKAREEMEE-HIQ-

General information: TITO was launched using: RESULT: Template: 2OY9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 248 -25758 -103.86 -310.33 target 2D structure prediction score : 0.86 Monomeric hydrophicity matching model chain A : 0.84 3D Compatibility (PKB) : -103.86 2D Compatibility (Sec. Struct. Predict.) : 0.86 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.630

(partial model without unconserved sides chains): PDB file : Tito_2OY9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OY9-query.scw PDB file : Tito_Scwrl_2OY9.pdb: