Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MITFLPII------FSILVVVTF-----VIGNFANGFIALVNST---EWVKRQKISFADQ-IVTALAVSRV-GLLWVLLLNWYSTVLNPAFCSVELRTTAYNIWAVTGHFSNWPATSLS-----IFYLLKIAN----FSNLIFLRLKRRVKSVILVVLLGPLLFLACHLFVVNMNQIVWTKEYEGNMTWKIKLRRAMYLSDTTVTMLANLVPFTVTLISFLLLVCSLCKHLKKMQLHGKGSQDPSTKVHIKVLQTVISFFLLRAIYFVSVIISVWSFKNLENKPVFMFCQAIGFSCSSAHPFILIWGNKKLKQTYLSVLWQMRY- 2W18 Chain:A ((24-356)) NLQLVSELKNPSGSCSVDVSAMFWEKEPCIITACEDVVSLWKALDAWQWEKLYTWHFAEVPVLQIVPVPDVYNLVCVALGNLEIREIRALFCEKQVLLKSGNIKAVLGLTKRRLVSSSGTLSDQQVEVMTFAEDGGGKENQFLMPPEETILTFAEVQGMQEALLGTTI-----MNNIVIWNLKTGQLLKKMHIDDASVCHKAYSEM--GLLFIVLSPVFQLIVINPKTTLSVGVMLYCLPPGQAGRFLEGDVKDHCAAAILT------SGTIAIWDLLLGQCTALLPPVQHWSFVKWSGTDSHLLAGQKDGN------IFVYHYS

General information: TITO was launched using: RESULT: Template: 2W18.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -303668 for 2238 contacts (-135.7/contact) + 2D Compatibility (PS) -29997 + (NN) 6197 + (LL) 2400 1D Compatibility (HY) -13600 + (ID) 2500 Total energy: -341168.0 ( -152.44 by residue) QMean score : 0.216

(partial model without unconserved sides chains): PDB file : Tito_2W18.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2W18-query.scw PDB file : Tito_Scwrl_2W18.pdb: