Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLD-LDFIAKLYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKRLEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIE---GVSLFELQANQLKTLNHQS--------GHTIQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEG-KLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKTIQPK-PGESVGRLVNV--DCKDTVLEYSELDPEVAN----------QFNNANIGIHAFKLGFILNAVN------RELPYHLAIKNLKQLDENFGVIE---QPT-LKFELFYFDIFTYG--TSFVTLQVPREEEFSPLKNKEGKD--SVATATEDLRRMGLI 2YQC Chain:A ((7-444)) QQIIDSFKQANQDQLFQYYDSLTIDQQQEFIDQLSTIEEPAKLISTVEQAIQFSQ-SRNFTQLPNEQTASTLDLSKDILQNWTELGLKAIGNGEVAVLLMAGGQGTRLGSSAPKGCFNIELPSQKSLFQIQAEKILKIEQLAQQYLKSTKKPIINWYIMTSGPTRNATESFFIENNYFGLNSHQVIFFNQGTLPCFNLQGNKILLELKNSICQSPDGNGGLYKALKDNGILDDLNSKGIKHIHMYCVDNCLVKVADPIFIGFAIAKKFDLATKVVRKRDANESVGLIVLDQDNQKPCVIEYSEISQELANKKDPQDSSKLFLRAANIVNHYYSVEFLNKMIPKWISSQKYLPFHIAKKKIPSLNLENGEFYKPTEPNGIKLEQFIFDVFPSVELNKFGCLEVDRLDEFSPLKNADGAKNDTPTTCRNHYLERSSK

General information: TITO was launched using: RESULT: Template: 2YQC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -123033 for 3111 contacts (-39.5/contact) + 2D Compatibility (PS) -43286 + (NN) -21188 + (LL) 52 1D Compatibility (HY) -28400 + (ID) 6350 Total energy: -222205.0 ( -71.43 by residue) QMean score : 0.508

(partial model without unconserved sides chains): PDB file : Tito_2YQC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2YQC-query.scw PDB file : Tito_Scwrl_2YQC.pdb: