Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRYLTAGESHGPSLTAIIEGIPAGLKLSAKDINEDLKRRQGGYGRGNRMKIETDQVIISSGVRHGKTLGSPITLTVTNKDHSKWLDIMSVEDIEERLKQKRRIKHPRPGHADLVGGIKYRFDDLRNALERSSARETTMRVAIGAIAKRILKE-IGIEIANHIVVFGGKEITVPDKL-TVQQ------IKVLSSQSQVAIVNPSFEQEIKDYIDSVKKAGDTIGGVIETIVGGVPVGLGSYVHWDRKLDAKIAQAVVSINAFKGVEFGLGFKSGFLKGSQVMDSISWTKDQGYIRQSNNLGGFEGGMTNGEPIIVRGVMKPIPTLYKPLMSVDIDTHEPYRATVERSDPTALPAAGVVMEAVVATVLVTEVLEKFSSDNMYELKEAVKLYRNYVNHF 1R53 Chain:A ((8-371)) FRVTTYGESHCKSVGCIVDGVPPGMSLTEADIQPQLTRRRP------------DRVEIQSGTEFGKTLGTPIAMMIKN-------------------------------------------------------RETIGRVASGAIAEKFLAQNSNVEIVAFVTQIGEIKMNRDSFDPEFQHLLNTITREKVDSMGPIRCPDASVAGLMVKEIEKYRGNKDSIGGVVTCVVRNLPTGLGEP--CFDKLEAMLAHAMLSIPASKGFEIGSGFQGVSVPGSKHNDPFY-------RTKTNNSGGVQGGISNGENIYFSVPFKSV-----------------------RHDPAVTPRAIPIVEAMTALVLADALLIQKARDFS-----------------

General information: TITO was launched using: RESULT: Template: 1R53.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -148873 for 2245 contacts (-66.3/contact) + 2D Compatibility (PS) -29858 + (NN) -18406 + (LL) 7264 1D Compatibility (HY) -14000 + (ID) 4900 Total energy: -208773.0 ( -92.99 by residue) QMean score : 0.486

(partial model without unconserved sides chains): PDB file : Tito_1R53.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1R53-query.scw PDB file : Tito_Scwrl_1R53.pdb: