Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKTMSAITAAAAVTSCFTGFGAASFSAPAKAAAQTNTLSENTNQSAAELVKNLYNTAYKGEMPQQAQGLTINKSTKGDVHAAFGEPERPVGGDNR---FDLYHWNMGQPGYGFSYHKDMTISEIRYFGTGVERQLNLGGVTPEVL---QKQLGPVNR-VLTVPFTDEIDYVYDTGRYELHFVIGTDQTADHVNLKAK 4DY5 Chain:A ((1-111)) -------------------------------------------------------------------------TGKNVNVEFDKGQNSARYSGVIKGYDYDTYNFQA-RKGQKVHVSISNEGADTYLFGPGISDSVDLSRYSSELDGNGQYTLPASGKYELKVLQTRNEARKNKAKKYSVNIQIK-------------

General information: TITO was launched using: RESULT: Template: 4DY5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 466 -27294 -58.57 -262.44 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -58.57 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.232

(partial model without unconserved sides chains): PDB file : Tito_4DY5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4DY5-query.scw PDB file : Tito_Scwrl_4DY5.pdb: